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The second hospital of Jilin University

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ZHU Zhicheng

DEPARTMENT: Cardiovascular Surgery Department

Introduction

  Contact Information:

  Postal Code: 130041

  Address: Department of Cardiovascular Surgery, NO.218 Ziqiang Street, Nanguan District, Changchun, Jilin Province, China.

  Telephone: +86-0431-88796793

  Fax: +86-0431-88934741

  E-mail: zhu5wolf@hotmail.com

  Title: Deputy chief physician, Associate Professor

  Medical Specialities:

  Coronary heart disease and Myocardial infarction: CABG or OPCABG, Surgical ablation for atrial fibrillation: modified Maze procedure, Valve replacement、Valvuloplasty , Great vessels diseases treatment, Cardiac trauma、Cardiac tumor, Minimally invasive treatment of heart disease, Surgery for complex congenital heart disease, Conventional congenital and acquired cardiovascular disease surgery.

  Major Research Direction:

  Mechanism of myocardial infarction, Inhibition of vascular hyperplasia, Regeneration of cardiovascular graft, Myocardial ischemia reperfusion injury, Diagnosis and treatment of great vessels diseases, Treatment of end - stage heart disease.

  Clinical Medical Practice:

  Participated in more than 700 operations on cardiovascular diseases every year including the first heart transplantation in Jilin Province, the first operation of repairment of the fistula on coronary artery and ventricle, right coronary artery angioplasty, the first domestic Off-Pump Coronary Artery Bypass Graft and Bipolar Radiofrequency Ablation Modified Maze Ⅲ Operation for Atrial Fibrillation, video-assisted mini-thoracotomy operation, undergoing correction of complicated congenital heart disease, surgical treatment for Great vessels diseases and so on. Multiple medical technologies have filled the gap of related fields in the province and China, reaching domestic and even international advanced level.

  Research and Teaching Contributions:

  Undertook one program of provincial science and technology development plan, one basic research project of Jilin University, one NSFC, one branch project of national three-phase ‘211’ construction project, three technology-supporting projects for national Twelve Five-Year Plan, three international scientific and technological cooperation projects of Jilin Province’s scientific development plan, 9 provincial-level projects and four other projects. Obtained two national patents, one Jilin Province natural science academic achievement award, eight 2nd prizes and five 3rd prizes of Jilin University’s medical achievements. Published one book and more than 40 papers including Articles Collected by SCI. Undertake theoretical and practical teaching tasks both for undergraduates and postgraduate students every year.

  Social Appointments:

  1. Standing Committee Member and Academic Secretary, Cardiovascular Surgeon Branch, Jilin Physicians' Association.

  2. Standing Committee and academic secretary, Cardiovascular Surgery Branch,Jilin Medical Association.

  3. Committee, Cardiovascular Surgery Branch, Jilin Medical Association.

  Potential Cooperation of Research:

  Mechanism of myocardial infarction, Inhibition of vascular proliferation, Regeneration of cardiovascular graft, Myocardial ischemia reperfusion injury, Diagnosis and treatment of great vessels diseases, Treatment of end - stage heart disease.

  Major achievements:

  Medical Book:

  , People’s Military Medical Press, August 2007.

  Publications:

  1. Zhicheng Zhu, Xiaomei Zheng, Dan Li, Tiance Wang, Rihao Xu, Hulin Piao, Kexiang Liu*; Prx1 promotes the proliferation and migration of vascular smooth muscle cells in a TLR4-dependent manner; Molecular Medicine Reports; 2016.12.6.IF:1.559.

  2. Zhicheng Zhu, Rihao Xu, Xiaomei Zheng, Tiance Wang, Dan Li, Yong Wang, and Liu Kexiang*; Inhibitory Effect of TLR4 Gene Silencing on Intimal Hyperplasia of Vein Grafting, Vascular and Endovascular Surgery; 2016.09.28.IF:0.662.

  3. Zhicheng Zhu, Yong Wang, Rihao Xu, Dan Li, Tiance Wang, Bo Li, Shudong Zhang and Kexiang Liu*; Giant aneurysm of the left main coronary artery with fistulous communication to the right atrium; Journal of Cardiothoracic Surgery; 2015.09.11,10:117.IF:1.03.

  4. Dan Li, Weitie Wang, Zhicheng Zhu, Yuefeng Wang, Rihao Xu and Kexiang Liu*; Cardiac lipoma in the interventricular septum:a case report; Journal of Cardiothoracic Surgery; 2015.05.09,10:69.IF:1.03.

  5. zhi-Cheng Zhu, Mei Sun, Xing-yi Zhang, Ke-Xiang Liu* et al; Expression and Characterization of Catalytic Domain of T Cell Protein Tyrosine Phosphatase(TC-PTP)-Immunohistochemical Study of TC-PTP Expression in Non-small Cell Lung Carcinomas; Chem Res Chinese; 2007:23(3):289-296.IF:0.363.

  6. Cuilin Zhu, Tiance Wang, Zhicheng Zhu, and Kexiang Liu*; Aberrant origin of left subclavian artery from the pulmonary artery and right aortic arch in an aortopulmonary window; Interactive Cardiovascular and Thoracic Surgery; 2016.8.1.IF:1.155.

  7. Haibin Zhang, Weitie Wang, Dan Li, Zhicheng Zhu, Tiance Wang, Rihao Xu and Kexiang Liu*; Undifferentiated sarcoma originating from the mitral valve:a case report; Journal of Cardiothoracic Surgery; 2016.05.04,11:82.IF:1.036.

  8. Duo Zhao, Zhicheng Zhu, Dan Li, Rihao Xu, Tiance Wang, and Kexiang Liu*; Pioglitazone Suppresses CXCR7 Expression To Inhibit Human Macrophage Chemotaxis through Peroxisome Proliferator-Activated Receptor γ; Biochemistry; 2015.11, 54(45):6806–6814.IF:3.015.

  9. Dan Li, Zhicheng Zhu, Xiaomei Zheng, Yong Wang, Yuefeng Wang, Rihao Xu, Tiance Wang and Kexiang Liu*; Surgical treatment of anomalous left coronary artery from pulmonary artery in an adult; Coronary Artery Disease; 2015.12,26:723-725.IF:1.302.

  10. Shuang Hao, Rihao Xu, Dan Li, Zhicheng Zhu, Tiance Wang, Kexiang Liu*; Attenuation of Streptozotocin-Induced Lipid Profile Anomalies in the Heart, Brain, and mRNA Expression of HMG-CoA Reductase by Diosgenin in Rats; Cell Biochemistry and Biophysics; 2015.01.29,72:3:741-749.IF:2.38.

  11. Guilin Yang, Nan Zhang, Tiance Wang, Shudong Zhang, Rihao Xu, Zhicheng Zhu and Kexiang Liu*; Liquid chromatography–tandem mass spectrometric assay for the determination of vaccarin in rat plasma: application to a pharmacokinetic study; Biomedical Chromatography; 2014.12;28(12):1789-94.IF:1.662.

  12. Rihao Xu#, Tiance Wang#, Dan Li, Zhicheng Zhu, Shudong Zhang, Chengluan Xuan, Wen Yan and Kexiang Liu*; Surgical approach for the treatment of aortoesophageal fistula combined with dual aortic aneurysms:a case report; Journal of Cardiothoracic Surgery; 2013.11.04,8:206.IF:1.187.

  13. Jianbin Sun, Jinhua Zheng, Kaitelynne H ling, Keyan Zhao, Zhongshang Xie, Bo Li, Tiance Wang, Zhicheng Zhu, Amit N Patel, Weiping Min, Kexiang Liu* and Xiufen Zheng*; Preventing intimal thickening of vein grafts in vein artery bypass using STAT-3 siRNA; Journal of Translational Medicine; 2012.01.04,10:2,IF:3.508.

  Patent:

  1. Artificial blood vessels with stent-graft, NO.ZL 2014 2 0462262.5.

  2. Acvanced stent-graft artificial blood vessels, NO.ZL 2014 2 0462261.0.

  Scientific Research Projects:

  1. Research of calcium channel of atrial cardiomyocyte on atrial fibrillation, science and technology development projects of Jilin Province, NO.201215084.

  2. Silence STAT3’s suppressing function for vascular graft hyperplasia by RNAI. Basic research projects of Jilin University, NO.201003017.

  3. The mechanism of toll-like receptors in the proliferation of transplanted vein endangium, National Natural Science Foundation of China (NSFC), NO.81170182.

  4. The development of traditional pathology, frontier pathology and regenerative medicine, the 3rd phase construction projects of the National 211 Project.

  5. Detection, prevention and key therapeutic technics of cardiovascular disease and its risk factors - reserch on key therapeutic technics on critical ischemic heart disease, the National ‘Twelfth Five’ Science and Technology Support Plan, NO.2011BAI11B18.

  6. Detection, prevention and key therapeutic technics of cardiovascular disease and its risk factors - reserch on the individualization and the standard of low level anticoagulant therapy after valve heart disease operation, National ‘Twelfth Five’ Science and Technology Support Plan, NO.2011BAI11B21.

  7. The research of improvement of Coronary heart disease: Coronary artery bypass grafting. National ‘Twelfth Five’ Science and Technology Support Plan, NO.2013BAI09B01.

  8. The mechanism of miRNA-711 in Ischemia - reperfusion injury. international cooperation projects of science and technology development projects of Jilin Province, NO.20160414054GH.

  9. The mechanism of boiled lentils extraction on ang II induced hypertrophy and hypertension, international cooperation projects of science and technology development projects of Jilin Province, NO.20110718.

  10. Stem cell engineering technology on the regeneration of cardiovascular grafts. international cooperation projects of science and technology development projects of Jilin Province, NO.20070720-2.

  11. The influences of GDF-15 in Heart transplantation immune rejection. The Finance Department of Jilin Province.

  12. The investigation and analysis of aortic dissection in etiology. The Finance Department of Jilin Province.

  13. The therapeutic strategies on aortic dissection and aneurysm. The Finance Department of Jilin Province.

  14. The application and popularization of the advanced artificial vascular stents on the treatment of type A aortic dissection. The special projects on industrial technology research and development of Jilin Province, NO.2013C023-4.

  15. The development and popularization of the therapeutic strategies of type A aortic dissection. Science and technology development projects of Jilin Province, NO.20130206025SF.

  16. The research of interference of miRNA in STAT3 suppressing Vascular graft hyperplasia. science and technology development projects of Jilin Province, NO.201115072.

  17. The mechanism of the expression and regulation of growth factor-5 on myocardial infraction. science and technology development projects of Jilin Province, NO.200905196.

  18. Tissue engineering and angiogenesis technology on the regeneration of vein system grafts. Science and technology development projects of Jilin Province, NO.200705196.

  19. Improved MazeIII bipolar radiofrequency modified maze treat atrial fibrillation. science and technology development projects of Changchun city, NO.08SF10.

  20. Building case base for Cardiothoracic Surgery graduate students. The program of building case base for Cardiothoracic Surgery graduate students of Jilin University.

  21. The effect and safety of levosimendan on the left ventricular failure after cardiovascular surgery. Affiliated research projects.

  22. The effect and safety of natriuretic peptide on the prevention of acute decompensated heart failure or pulmonary hypertension-Clinical Trails. Affiliated research projects.

  23. The effect of natriuretic peptide - lyophilized recombinant human brain natriuretic peptide on the perioperative of cardiovascular surgery. Affiliated research projects.

  Medical achievement awards:

  1. The research of interference of miRNA in STAT3 suppressing Vascular graft hyperplasia. The excellent prize of natural science academic achievement award of Jilin Province.

  2. Stented elephant trunk in direct vision treat aortic dissection. Second prizes of medical achievement of Jilin University.

  3. One - way valve pericardium patch treat atrial septal defect with severe pulmonary hypertension. Second prizes of medical achievement of Jilin University.

  4. Improved MazeIII bipolar radiofrequency modified maze treat atrial fibrillation. Second prizes of medical achievement of Jilin University.

  5. Stented elephant trunk in direct vision treat descending aortic aneurysm combine esophageal fistula. Third prizes of medical achievement of Jilin University.

  6. The application of minimally invasive cardiac surgery in Cardiovascular Surgery. Third prizes of medical achievement of Jilin University.

  7. The application of improved Bentall in aortic root surgery. Third prizes of medical achievement of Jilin University.

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